INSTITUTE OF SCIENCE
AIDS -- THE RIDDLE SOLVED
ITS MICROBIAL CAUSE AND THERAPY
A Typical "Oral-Focal" Disease?
A Proven Autogenous Vaccine-Therapy
HIV-AIDS Controversy Resolved
by S. H. Shakman
Copyright 1996-1998, all rights
"It can be said, regarding Medicine, that one who knows only
How can it be, in the presumably brilliant intellectual climate of
1997, that two groups of well-respected medical and scientific
experts have essentially opposite views on the role of HIV in AIDS?
On the one hand, influential researchers including Anthony Fauci of
the National Institutes of Health and Robert Gallo of claimed HIV-
discovery fame assert that HIV causes AIDS; on the other hand, a
number of equally creditable researchers, including Peter Duesberg
of U.C. Berkeley and Nobel laureate Carey Mullis of U.C. San Diego,
assert that HIV does not cause AIDS. Neither position is based on
frivolous conjecture; both groups
essentially KNOW that they are right. And essentially, they may
be, if, as appears with ever-increasing certainty, AIDS is a
typical "oral-focal" disease.
current information about Medicine does not even know that."
(SIR WILLIAM OSLER, in J. F. A. McManus, The Fundamental Ideas
of Medicine, Charles C. Thomas, Springfield, Ill., 1963, p.6)
AIDS - A Typical "Oral-Focal" Disease?
Similarities between AIDS and MS
[*1] have long
been recognized, prompting the hope that future advances in AIDS
research might benefit investigations into MS and other presumably
[*2]. Ironically, a long-ignored monumental
body of work by the late Dr. Edward C. Rosenow.
of the Mayo Foundation, involving MS and other diverse
diseases, may hold the keys to unravelling the many mysteries
surrounding the syndrome known as AIDS.
During an active professional career spanning more than a half-
century and including nearly three decades with the Mayo
Foundation (1915-1944), Dr. Rosenow detailed the role of bacteria
(and/or their derivatives) emanating from "oral foci" in the
causation of MS and a wide range of other diseases. This work
included reference to disease of "blood-building tissues" [*3], a condition
which might be interpreted as related to modern-day AIDS. Beyond
this nice coincidence, some particularly important recent advances
in understanding AIDS provide a seemingly decisive link to Dr.
Rosenow's emphasis on the role of oral foci in systemic disease:
In the early years of the age of AIDS, initial infection by the
organism that causes AIDS was thought to be followed by a long
period of dormancy, prior to the actual outbreak of full-blown
AIDS. However, this view has been replaced in recent years by the
realization that the AIDS organism is actively replicating during
the long period between infection and visible onset of disease, and
both tonsils and teeth [*4] have been
reservoirs for this replication process. Aside from specific
designation as a "reservoir", or source for more generalized
infection, numerous reports address oral or dental manifestations
[*5] as an
early indication of HIV infection.
- Until very recently, one of the major assumptions that has guided
AIDS research was the so-called antigenic-diversity theory, whereby
it was thought that the ravages of AIDS might be
attributed to a continually mutating virus population which kept a
step ahead of the body's defenses. However, recent work
published in the authoritative journal SCIENCE
that progression of AIDS is associated not with a mutating virus
population, but rather with a stable one that is "replicating in a
constant environment". While this refutes the "antigenic
diversity" hypothesis (and apparently devalues the research
industry that has grown up around it), all is not lost; this new
finding is fully consistent with the hypothesis that AIDS is a
typical so-called oral-focal disease.
A Proven Autogenous Vaccine-Therapy
Dr. Rosenow's work emphasized the primary importance of the
removal of offending foci [*7], but
cautioned that this action may not alone be sufficient to halt
disease processes in cases where secondary foci are become well-
established. However, Dr. Rosenow employed therapeutic vaccines
which reportedly worked wonders
numerous patients with various conditions. If the disease
condition known as AIDS is correctly grouped with conditions with
which Dr. Rosenow worked, we may expect similar results. This in
turn may serve to revive public awareness of the depth and broad
scope of Dr. Rosenow's
contributions to understanding and combatting human disease.
In the case of AIDS, the proper use of Dr. Rosenow's methods
would be expected to yield the pathogenic phase of the causative
organism of AIDS (as demonstrated by Dr. Rosenow in so many other
organism would be capable of replicating the disease conditions in
laboratory animals (the lack of a so-called "animal model" for AIDS
has been cited as a key factor inhibiting AIDS research [*9]); and
also serving as the foundation for highly specific therapeutic
Regarding a program of therapy for AIDS, beyond the indicated
removal of offending oral foci of infection, particular attention
may be given to Dr. Rosenow's regimen of
"vaccine" (antigen) and antibody against MS
At first glance, the hypothesis of AIDS as a typical "oral-focal"
disease may seem far removed from the continuing
controversy over the relationship between AIDS and HIV; in
reality, the latter is readily explained by
HIV-AIDS Controversy Resolved
Over the past several years, the conventional view that HIV is
related to the cause of AIDS has been challenged by a small but
reputable group of scientists, notably Dr. Peter Duesberg of
Berkeley who maintains that HIV is too weak to cause AIDS. In
accord with the works of Dr. Rosenow, the entity commonly found to
be associated with AIDS, HIV, could be a dissociative form or
invasive phase of a pathogenic streptoccal form, or both. Such
dissociations and possible reversions to parent forms, under
favorable conditions, have been discussed by several workers up to
the present [*11].
Specifically, in the case of the HIV-AIDS controversy, Dr.
Rosenow's methodology for effecting dissociation of streptococcal
forms into filtrable (viral) forms [*12]
expected to yield a filtrable phase of the AIDS organism. Should
this be found to be HIV and the process demonstrated as reversible,
this would show (a) how HIV might comprise an essential invasive
phase of the organism that conveys AIDS, but, at the same time, (b)
explain why this same HIV (phase) itself is apparently incapable of
directly causing AIDS. The possibly-common occurrence of
reversible dissociation of bacterial species) has been
prominently documented, from early in the century. [*13]
Pending the establishment of mechanisms for proper production of
therapeutic (S. rosenow) vaccines in accord with Dr. Rosenow's
methodology, an immediately available interim measure that might be
utilized is "autohemotherapy" in its original and predominant form
- the prompt intramuscular or subcutaneous reinjection of
autologous (one's own) whole blood
[*14]. Regardless of the identity or source
of the organism that causes
AIDS, it is known that some form of the causative organism is in
the blood; thus, as first suggested by Cuyugan in 1988
autohemotherapy would be expected to have therapeutic value,
presumably acting to some extent as an autogenous vaccine. It is
noted that a more
complex, experimental form of autohemotherapy [*16]
proposed for AIDS, seemingly paving the way for trials of the
simpler original method.
This article is an electronic preprint of a paper to be proposed to
the Journal of Infectious Disease, in which journal Dr.
Rosenow published some 53 articles spanning the period 1904-1945.
For further information on Dr. Rosenow's work, as well as specific
documentation supporting the hypothesis of AIDS as a typical focal
disease, please consult Reference Manual Rosenow Et Al -- medical
guide of the future, by
First posted at www.geocities.com/athens/3361 in 1996; reposted
here 23 October 1998.