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AUTOHEMO FOR HERPES ZOSTER - BACKGROUND/IMPETUS 57C3
Ansfield and Rens, 1956 [57C3], 1319, note "Van Blarrim and
Horax [JAMA 161 (1956):511-515] have recently described the
radical surgery, from lobotomy to chordotomy, that has been done
in an attempt to relieve the suffering from this agonizing
neuralgia. ...
"Among the newer methods of treatment of herpes zoster,
including the use of Chloromycetin or Aureomycin, is the use of
gamma globulin; a very interesting report describing the
effective treatment of 5 patients with this method was made by
Weintraub [JAMA 157 (1955):1611]. In 1942, J.W. Nixon-Davis,
M.D., of Chicago, informed one of us (JLR) that injecting a
patient's own blood intramuscularly was the treatment of choice
in dealing with herpes zoster."
AUTOHEMO FOR HERPES ZOSTER: SAFETY/EXPENSE 57C3
Ansfield and Rens [57C3], p. 1320, "There were no reactions
from autohemotherapy other than some local discomfort at the site
of the infection; and there is no expense to the patient for his
own blood ... "
AUTOHEMO TECHNIC 57C3
[57C3] "... we have treated 54 cases of herpes zoster by
intramuscular injections of 15cc of the patient's own blood. ...
At the time the diagnosis [of herpes zoster] was made, 15cc of
blood was withdrawn from the antecubital vein of the patient and
injected deep into the gluteal muscle on one side. the patient
was instructed to return in 48 hours. If the pain had entirely
subsided no further treatment was given. Eight patients were in
this category. The response of the vesicles went hand in hand
with that of the subjective symptom of pain. On the second
visit, if the patient still had pain, a second injection of 15cc
of his blood was given in the opposite gluteal muscle, and he was
instructed to return in 48 hours. If the pain had subsided then,
no further treatment was given. 34 patients were cured after
this second injection. After 2 such injections at 48 hour
intervals, 12 patients still had painful herpes zoster and were
given a third injection of 15cc of their blood and instructed to
return again in 48 hours. In 10 of these 12 patients requiring a
third injection, the pain had subsided and the vesicles were
clearing rapidly,; but 2 patients failed to respond to all 3
injections. One of these patients was given 2 injections of 1000
micrograms of vitamin B12, which apparently cleared the pain
promptly." The final patient did not respond to vitamin B12, but
the pain gradually subsided over the next 3 months.
In summary, "The results were most gratifying in 52 cases, with
the pain entirely controlled within 2 to 7 days. We feel that
these results are unsurpassed and heartily urge that
autohemotherapy be used routinely in treating herpes zoster."
AUTOHEMO SAFETY/COST 57C3
[57C3] p. 1320, "There were no reactions from autohemotherapy
other than some local discomfort at the site of the injection;
and there is no expense to the patient for his own blood, in
contradistinction to the high cost of gamma globulin or
moderately high cost of broad-spectrum antibiotics."