STREPTOCOCCI AS SOURCE OF TOXINS IN EPILEPSY AND SCHIZOPHRENIA 53R1


  "The results in animals support the view generally held that the


seizures in epilepsy and certain symptoms in the psychoses,


including schizophrenia, are of toxic origin and that the


respective specific neurotoxins may in fact be derived from


specific types of streptotocci.  Furthermore, the studies suggest


that the tissues for which the 'neurotoxin' or streptococci have


predilection may become hypersensitive or allergic so that


extremely small amounts of the 'neurotoxin', too small to be


detected by chemical methods or small numbers of the streptococci,


suffice to produce the respective characteristic symptoms. [53R1]






ANIMALS AND HUMANS: SIMILAR TISSUES - AND INTUITION   [53R1, 422]


  In 1953 Dr. Rosenow shared some rather remarkable overview


observations on the physiology and mentality of laboratory animals: 


  "The results obtained in these studies in a way transcend the


importance of streptococci and their specific toxins in the


causation of disease for they indicate how much alike the functions


and underlying organic constitution of the respective tissues of


experimental animals and that of human beings are.  From long


observation of inoculated and well animals, much evidence has been


found to indicate that their intuitive and acquired responses to


external stimuli and stresses of life are also similar, as


indicated especially by the following observations in the behavior


of white mice.  They practice sanitation and immunization seemingly


by intuition.  With 10 or 12 in a cage (10 x 12 x 10") they


normally sleep in a huddle, often 2 or 3 deep, as far away as


possible from the area where excreta are deposited.  The mice that


become ill are not allowed in the huddle or they voluntarily remain


apart and are not molested while life lasts.  But after death, the


well mice if cannibalistic almost invariably eat the diseased


organ, such as pneumonic lungs produced by cerebral and/or nasal


inoculation of 'pneumotropic' streptococcus or virus of influenza. 


In sharp contrast if death was due to encephalitis following


inoculation of the streptococcus or virus of encephalitis, they


remove the skull and eat the diseased brain."


  "I humbly present the results of these studies in deep


appreciation of the thrills which I have had as ideas which have


come to me were substantiated by experiments of trial and error." 


 [53R1, 422]