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Copyright 1995-2001 S.H. Shakman, Institute Of Science; all
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AUTOHEMO: ANTICOAGULANTS DENOUNCED 38A16
Dean [38A16, 784] in his article on intravenous
autohemotherapy, notes that "Descarpentries emphatically
denounces the use of anticoagulants, claiming that any substance
that disturbs the physiologic functions of the blood to the point
of preventing coagulation, must equally disturb other functions
whose aim it is to defend the organism against infection."
AUTOHEMO, IV WITH HEMOLYSED BLOOD, AND MALARIA THERAPY 38A16
Dean 1938 [38A16] , The realization that artificially induced
malaria infection might bring about benefit in some cases of
neuro-syphilis had fostered "the modern vogue of treating
neurosyphilis with mechanical hyperpyrexia" (induction of fever).
Dean 1938 [38A16], 775-6, sought ot improve on this by
duplicating another aspect of the "mechanism of malaria", blood
destruction, to be used in conjunction with artificial induction
of fever. While his is thought to be the first attempt to
combine the two components of induced fever and hemolyzed
autoblood, he discusses some earlier works from 1923 to 1926
involving hemolyzed autoblood: Descarpentries (1923, 1926) had
lysed 10cc of blood in 20cc distilled water, agitated the mixture
with marbles, and injected the resultant clear fluid
subcutaneously; Zimmerman, 1923, added 2cc of water to 20 cc
autoblood and immediately reinjected it intramuscularly or
intravenously; and Brunner and Breuer, 1924, placed 14cc water in
a 20cc syringe, aspirated venous blood into the same syringe to
capacity, and immediately reinjected the mixture without drawing
the needle out of the vein.
Dean [38A16], p. 776, "Descarpentries employs distilled water
and blood in a proportion of 2:1, lysing 10cc uncitrated blood in
20cc distilled water; he then agitates the mixture in a flask
containing several marbles, about which the clumps of fibrin
adhere; finally he injects the clear fluid subcutaneously in
divided doses - a momentarily painful, but according to him, a
very beneficial procedure in various septic conditions."
Dean [38A16], p.778, [Notwithstanding Descarpentries'
admonitions to the contrary,] Dean mixed 1 part sodium citrate
and 9 parts blood (10-50cc), shaken for 5 minutes, added 15 parts
of distilled water, agitated again for 5 minutes, and reinjected
intravenously (26-150cc total)