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Copyright 1995-2001 S.H. Shakman, Institute Of Science; all
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AUTOSEROTHERAPY: INITIAL SKEPTICISM OF ONE CONVERT - 14H3
Gottheil and Saterstein [14H3] relate "It was with considerable
skepticism that we read the reports that have been published
during the last year or two concerning the treatment of certain
dermatoses with serum, autogenous or foreign; and the more so
since these reports were in some cases of that very rosey hew
which we have learned to know as the reflection of the subjective
illumination of the observer. ...
AUTOSEROTHERAPY METHOD - 14H3
From 40-200 cc blood is removed, usually the larger amount,
allowed to clot for about 10 minutes, broken up with a glass rod
and centrifuged at about 5000 rpm for 30-40 minutes. 40-45% of
the blood drawn is recovered as serum, and reinjected in a vein
unually on the opposite side from that drawn.
AUTOSEROTHERAPY, SAFETY OF - 14H3
"We have now given over 250 of these autoserum injections,
without seeing, save in a single case, any contra-indications to
their employment. ... The one exception was in a very bad case of
gangrenous radiodermatitis in a case of leukemia in which the
patient did marvelously well under the first four, but had a
reaction, and chills followed by fever after the 5th and 6th ....
[Nonetheless] the result here was not to be described as
otherwise than astounding. ... The patient [previously] was
apparently in a hopeless condition .... at present the patient is
perfectly well and attending to his business ..."
AUTOSEROTHERAPY, RESULTS OF - 14H3
AUTOSERO: PSORIASIS - 14H3
AUTOSERO: URTICARIA - 14H3
AUTOSERO: ACNE - 14H3
AUTOSERO: LICHEN PLANUS - 14H3
AUTOSERO: FURUNCULOSIS - 14H3
Results in the other cases: In 12 cases of severe and
extensive psoriasis, following 4-6 injections at intervals of 5-7
days, "every lesion had disappeared," and cases of pustular acne,
urticaria, lichen planus and furunculosis had all improved.
AUTOSERO: SUSPECTED MECHANISM OF ACTION - EXTERIORIZATION -
14H3
"Blood serum is an extremely complex material, and it is
undoubtedly changed by its retention outside the body, by the
coagulation and centrifugation."
AUTOSEROTHERAPY AS BLOODLETTING - 14H3
"Is it possible that the good results attained [by autoserum in
psoriasis] are due to the bloodletting alone? The thought has
often struck me as it must have struck others, that the
generations of acute observers and habile clinicians who
practices bloodletting in so many affections cannot have been
entirely wrong; they must have seen some good result in some
cases at least. And there is at least one case of psoriasis on
record, to which our friend Dr. P. Brynberg Porter has called our
attention, in which the late Weir Mitchell in his young days,
being left in charge of a very bad case of psoriasis and not
knowing what to do, put the patient to bed and bled her everyday,
and cured her disease. Bloodletting alone, however, has been
tried, and has not given results. We do not think that the
benefits of this procedure can be ascribed to it."