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AUTOSERO: PSORIASIS - 14H2
In 1914 Fox [14H2] described the use of autogenous serum in the
treatment of 28 psoriasis patients, 17 females and 11 males, from
ages 11 to 54. Different forms of the disease were represented,
including "the guttae, mummular and diffuse" of varying grades of
severity.
AUTOSEROTHERAPY METHOD - 14H2
Fox's technic consisted of drawing 50cc of blood from the
cubital vein, centrifuge it at 1800 rpm, and when the serum was
thoroughly separated from corppuscles and fibrin, drawing it of
in a glass syringe and injecting it "without delay, either
intravenously or intramuscularly. The amount of serum obtained
varied between 15 and 25 cc. The entire procedure was completed
in under a half-hour. Generally at least 3 injections were
given, at intervals of from 3-5 days, each followed by local
application of a 10% chrysarobin ointment. [It is noted that Fox
used both intravenous and intramuscular reinjection.]
AUTOSEROTHERAPY RESULTS - 14H2
"The results of the treatment in general were very satisfactory
and in some of the cases decidedly brilliant." One psoriasis
patient characterized the results as "perfectly marvelous",
another "like magic"; particularly pleased was "a man who was
relieved of his psoriasis for the first time in 24 years."
AUTOSEROTHERAPY SAFETY, WITH VENOUS BLOOD - 14H2
"No ill effects from the serum treatment were observed except
in one case in which the 3rd injection was followed by a rather
violent urtivaria lasting a week. Urticarial rashes were also
observed by Linser in several cases, generally lasting from 12 to
24 hours [non-autogenous injections]. In the case of autogenous
serum injections, it is hardly conceivable that any serious ill
evvects could result when proper aseptic precautions were
observed.
AUTOSEROTHERAPY AS VENESECTION? - 14H2
"The idea naturally presents itself that the beneficial action
might be solely due to the bloodletting. That this therapeutic
measure may lessen the intensity of some inflammatory skin
diseases there can be no doubt; that the results obtained were
due, however, to the injections of the serum and not merely to
the venipuncture has been shown by comparative tests with the two
methods of treatment."